Detalhe da pesquisa
1.
Cell-Type-Dependent Recruitment Dynamics of FUS Protein at Laser-Induced DNA Damage Sites.
Int J Mol Sci
; 25(6)2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542501
2.
Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Hum Mol Genet
; 28(17): 2835-2850, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31108504
3.
The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 Motility.
Int J Mol Sci
; 22(5)2021 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33670886
4.
Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.
Acta Neuropathol
; 139(1): 99-118, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31642962
5.
Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
Neurobiol Dis
; 82: 420-429, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26253605
6.
FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Cell Rep
; 42(2): 112025, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696267
7.
Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons.
Cells
; 12(10)2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37408187
8.
Effects of digitalized university curriculum-associated teaching on the equilibrium of autonomic neurophysiology and disposition of learners in medical school (EDUCATE-AND-LEARN): protocol for a randomized crossover study.
Ann Med
; 53(1): 1991-1998, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34726527
9.
Concomitant gain and loss of function pathomechanisms in C9ORF72 amyotrophic lateral sclerosis.
Life Sci Alliance
; 4(4)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619157
10.
High content organelle trafficking enables disease state profiling as powerful tool for disease modelling.
Sci Data
; 5: 180241, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30422121
11.
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Stem Cell Reports
; 10(2): 375-389, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358088
12.
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Nat Commun
; 9(1): 335, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29362359